Mounjaro, eh!

The Pound of Cure Weight Loss Podcast

In Episode 7 of the Pound of Cure Weight Loss podcast, Dr. Matthew Weiner and co-host Zoe Schroeder, RD, dive into the latest developments in weight loss treatments, including GLP-1 medications for weight loss, the differences between gastric bypass vs. sleeve gastrectomy, and how to manage the side effects of GLP-1 weight loss drugs. This episode is packed with science-based guidance and actionable tips for your weight loss journey.

GLP-1 Medications for Weight Loss: Benefits Beyond the Scale

Dr. Weiner discusses GLP-1 medications like Wegovy (Semaglutide) and Zepbound (Tirzepatide), which are showing great success for weight loss. Beyond helping patients lose weight, these medications reduce the risk of cardiovascular diseases, such as heart attacks and strokes, by up to 25%. Additionally, research highlights the role these medications play in lowering cancer risks linked to obesity. GLP-1 medications not only suppress appetite but may have other positive effects on metabolism.

Side Effects of GLP-1 Weight Loss Drugs: What You Need to Know

While GLP-1 medications are effective, they do have side effects. Dr. Weiner and Zoe discuss nausea, vomiting, and gastrointestinal discomfort, common with medications like Wegovy and Zepbound. These side effects are due to the drug’s mechanism of slowing gastric emptying. Dr. Weiner advises starting with a low dose and eating small, well-balanced meals to minimize symptoms. More serious side effects like gallbladder issues and pancreatitis are rare but important to monitor.

Gastric Bypass vs. Sleeve Gastrectomy: Choosing the Right Bariatric Surgery

Dr. Weiner explains the key differences between gastric bypass vs. sleeve gastrectomy to help patients make informed decisions. He shares a patient story of a woman who initially tried GLP-1 medications but switched to gastric bypass due to severe side effects. Gastric bypass often results in more significant weight loss and is ideal for patients with severe acid reflux or those looking to avoid long-term medications, while sleeve gastrectomy is simpler but comes with a higher risk of weight regain and GERD.

Patient Success Story: From GLP-1 Medications to Bariatric Surgery

A patient in her 30’s transitioned from GLP-1 medications to a gastric bypass due to overwhelming side effects. Post-op, she achieved significant weight loss and resolved many issues caused by the medications. This story illustrates that some patients may prefer surgery when medication-related side effects impact their quality of life.

Nutrition Tip: High-Protein Lentil Pasta

Zoe shares a simple nutrition tip: adding lentil pasta to your diet. Lentil and chickpea pastas are high in protein and fiber, making them great options for bariatric and GLP-1 patients who need to eat smaller portions but still require nutrient-dense foods to support healing and weight loss.

Finally, Dr. Weiner and Zoe answer six questions from listeners including, whether or not Paxil causes weight gain, weight loss stalls on a Vegan diet, and supplement suggestions.

Conclusion: Finding the Right Weight Loss Solution for You

Episode 7 offers a comprehensive look at options like GLP-1 medications for weight loss and gastric bypass vs. sleeve gastrectomy. Whether managing side effects of GLP-1 weight loss drugs or considering surgery, Dr. Weiner and Zoe provide practical advice to help you make informed decisions on your weight loss journey.

Chapitres

1. Mounjaro, eh! (00:00:00)

2. In the News - Cardiovascular and Cancer Risk Reduced (00:01:07)

3. Patient Story - Patient developed cholecystitis (00:05:47)

4. Nutrition Segment - Lentil Pasta (00:09:31)

5. The Economics of Obesity - Mounjaro, Eh! (00:12:34)

6. Dosing for GLP-1's (00:17:21)

7. Metabolism Testing, Useful or Not? (00:22:23)

8. Paxil made me gain 30 pounds. Should I keep taking it? (00:27:33)

9. Supplement Suggestions (00:30:34)

10. Weight Loss Stall on a Vegan Diet (00:35:05)

11. The Risk of Thyroid Tumors and Pancreatitis on GLP-1's (00:40:31)