TdC 269: Clinicagens na trombocitopenia imune

Ta de Clinicagem

https://www.youtube.com/watch?v=6uT3TxGTJ0U

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Iaaaaaaago Jorge, Amyr Chacar e Gabriel Cunha trazem 5 clinicagens sobre trombocitopenia imune (PTI)!
1) Diagnósticos diferenciais de PTI
2) Quais exames solicitar para um paciente com PTI
3) Quando e onde tratar um paciente com PTI
4) Como tratar PTI
5) PTI no perioperatório

Referências:
1. Provan, Drew et al. “Updated international consensus report on the investigation and management of primary immune thrombocytopenia.” Blood advancesvol. 3,22 (2019): 3780-3817. doi:10.1182/bloodadvances.2019000812
2. Neunert, Cindy et al. “American Society of Hematology 2019 guidelines for immune thrombocytopenia.” Blood advances vol. 3,23 (2019): 3829-3866. doi:10.1182/bloodadvances.2019000966
3. Gasbarrini, A et al. “Regression of autoimmune thrombocytopenia after eradication of Helicobacter pylori.” Lancet (London, England) vol. 352,9131 (1998): 878. doi:10.1016/S0140-6736(05)60004-9
4. Vrbensky, John R et al. “The sensitivity and specificity of platelet autoantibody testing in immune thrombocytopenia: a systematic review and meta-analysis of a diagnostic test.” Journal of thrombosis and haemostasis : JTH vol. 17,5 (2019): 787-794. doi:10.1111/jth.14419
5. Li, Na et al. “Platelet variability index: a measure of platelet count fluctuations in patients with immune thrombocytopenia.” Blood advances vol. 5,20 (2021): 4256-4264. doi:10.1182/bloodadvances.2020004162
6. Mazzucconi, Maria Gabriella et al. “Prednisone vs high-dose dexamethasone in newly diagnosed adult primary immune thrombocytopenia: a randomized trial.” Blood advances vol. 8,6 (2024): 1529-1540. doi:10.1182/bloodadvances.2023010975
7. Wei, Yu et al. “High-dose dexamethasone vs prednisone for treatment of adult immune thrombocytopenia: a prospective multicenter randomized trial.” Blood vol. 127,3 (2016): 296-302; quiz 370. doi:10.1182/blood-2015-07-659656
8. Stasi, Roberto. “How to approach thrombocytopenia.” Hematology. American Society of Hematology. Education Program vol. 2012 (2012): 191-7. doi:10.1182/asheducation-2012.1.191
9. AM Donald, C Adam. Immune thrombocytopenia (ITP) in adults: Clinical manifestations and diagnosis. Uptodate.com acesso em dezembro/2024.
10. AM Donald, C Adam. Initial treatment of immune thrombocytopenia (ITP) in adults. Uptodate.com acesso em dezembro/2024.