Artwork

Contenu fourni par Healio, Adam J. Brown, and MD. Tout le contenu du podcast, y compris les épisodes, les graphiques et les descriptions de podcast, est téléchargé et fourni directement par Healio, Adam J. Brown, and MD ou son partenaire de plateforme de podcast. Si vous pensez que quelqu'un utilise votre œuvre protégée sans votre autorisation, vous pouvez suivre le processus décrit ici https://fr.player.fm/legal.
Player FM - Application Podcast
Mettez-vous hors ligne avec l'application Player FM !

The History of Steroids

19:21
 
Partager
 

Manage episode 407440447 series 3560282
Contenu fourni par Healio, Adam J. Brown, and MD. Tout le contenu du podcast, y compris les épisodes, les graphiques et les descriptions de podcast, est téléchargé et fourni directement par Healio, Adam J. Brown, and MD ou son partenaire de plateforme de podcast. Si vous pensez que quelqu'un utilise votre œuvre protégée sans votre autorisation, vous pouvez suivre le processus décrit ici https://fr.player.fm/legal.

Do you know which U.S. president had Addison’s disease? Or how rumors from WWII led to funding for research on cortisol? In this episode, take a trip down memory lane as we detail the history of steroids and the scientists whose work lead to the discovery of prednisone.

  • Intro :14
  • A query: What other disease is attributed to Thomas Addison? :40
  • Overview of the layers of the adrenal gland 1:18
  • History of the adrenal gland 2:10
  • Thomas Addison enters the scene 3:39
  • Kennedy and terminology 6:15
  • Charles Brown-Sequard helps describe function of adrenal glands 7:13
  • George Oliver and Edward Sharpey-Schafer help understand adrenal gland 8:44
  • Adrenaline is discovered 10:03
  • Steroid chemistry begins in earnest 10:14
  • Steroids discovered, but questions remain 10:25
  • WWII rumors spur research on cortin 11:15
  • Edward Calvin Kendall, Tadeus Reichstein and Philip Showalter Hench receive Nobel prize for their discoveries relating to the hormones of the adrenal cortex 12:23
  • Committee of 14 chemists assembled 14:24
  • 1948: The case of Mrs. G 15:21
  • Pharmaceutical companies race to produce cortisone 17:08
  • How we arrived at prednisone 17:43
  • The answer to the question: “What other disease was described by Thomas Addison?” 18:34

We’d love to hear from you! Send your comments/questions to rheuminationspodcast@healio.com.

References:

Benedek TG. Clin Exp Rheumatol. 2011;29:S-5-12.

Burns CM. Rheum Dis Clin North Am. 2016;doi: 10.1016/j.rdc.2015.08.001.

Lawrence L. Controversial ‘father’ of endocrinology: Brown-Séquard. Endocrine Today. February 2008. https://www.healio.com/endocrinology/news/print/endocrine-today/%7B0b1791e0-0e1c-42ac-bec3-d5b67bb054f6%7D/controversial-father-of-endocrinology-brown-squard. Accessed April 10, 2018.

Pearce JMS. J R Soc Med. 2004;97:297-300.

  continue reading

86 episodes

Artwork
iconPartager
 
Manage episode 407440447 series 3560282
Contenu fourni par Healio, Adam J. Brown, and MD. Tout le contenu du podcast, y compris les épisodes, les graphiques et les descriptions de podcast, est téléchargé et fourni directement par Healio, Adam J. Brown, and MD ou son partenaire de plateforme de podcast. Si vous pensez que quelqu'un utilise votre œuvre protégée sans votre autorisation, vous pouvez suivre le processus décrit ici https://fr.player.fm/legal.

Do you know which U.S. president had Addison’s disease? Or how rumors from WWII led to funding for research on cortisol? In this episode, take a trip down memory lane as we detail the history of steroids and the scientists whose work lead to the discovery of prednisone.

  • Intro :14
  • A query: What other disease is attributed to Thomas Addison? :40
  • Overview of the layers of the adrenal gland 1:18
  • History of the adrenal gland 2:10
  • Thomas Addison enters the scene 3:39
  • Kennedy and terminology 6:15
  • Charles Brown-Sequard helps describe function of adrenal glands 7:13
  • George Oliver and Edward Sharpey-Schafer help understand adrenal gland 8:44
  • Adrenaline is discovered 10:03
  • Steroid chemistry begins in earnest 10:14
  • Steroids discovered, but questions remain 10:25
  • WWII rumors spur research on cortin 11:15
  • Edward Calvin Kendall, Tadeus Reichstein and Philip Showalter Hench receive Nobel prize for their discoveries relating to the hormones of the adrenal cortex 12:23
  • Committee of 14 chemists assembled 14:24
  • 1948: The case of Mrs. G 15:21
  • Pharmaceutical companies race to produce cortisone 17:08
  • How we arrived at prednisone 17:43
  • The answer to the question: “What other disease was described by Thomas Addison?” 18:34

We’d love to hear from you! Send your comments/questions to rheuminationspodcast@healio.com.

References:

Benedek TG. Clin Exp Rheumatol. 2011;29:S-5-12.

Burns CM. Rheum Dis Clin North Am. 2016;doi: 10.1016/j.rdc.2015.08.001.

Lawrence L. Controversial ‘father’ of endocrinology: Brown-Séquard. Endocrine Today. February 2008. https://www.healio.com/endocrinology/news/print/endocrine-today/%7B0b1791e0-0e1c-42ac-bec3-d5b67bb054f6%7D/controversial-father-of-endocrinology-brown-squard. Accessed April 10, 2018.

Pearce JMS. J R Soc Med. 2004;97:297-300.

  continue reading

86 episodes

Tous les épisodes

×
 
Loading …

Bienvenue sur Lecteur FM!

Lecteur FM recherche sur Internet des podcasts de haute qualité que vous pourrez apprécier dès maintenant. C'est la meilleure application de podcast et fonctionne sur Android, iPhone et le Web. Inscrivez-vous pour synchroniser les abonnements sur tous les appareils.

 

Guide de référence rapide

Écoutez cette émission pendant que vous explorez
Lire