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Dry Humors, Part 1

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Manage episode 407440420 series 3560282
Contenu fourni par Healio, Adam J. Brown, and MD. Tout le contenu du podcast, y compris les épisodes, les graphiques et les descriptions de podcast, est téléchargé et fourni directement par Healio, Adam J. Brown, and MD ou son partenaire de plateforme de podcast. Si vous pensez que quelqu'un utilise votre œuvre protégée sans votre autorisation, vous pouvez suivre le processus décrit ici https://fr.player.fm/legal.

Try your hand at this medical mystery, which is followed by some didactics on a fascinating disease which will hopefully make sense of this inscrutable title.

Brought to you by GSK. Consider the long-term impact of disease activity, flares and corticosteroid use on patients with active SLE. Learn more now at treatfortodayandtomorrow.com

  • Intro :22
  • What to expect in each episode :30
  • The case: A 75-year-old man with Sjogren’s and MALT lymphoma presents with recurrent cerebral infarcts of multiple territories 1:10
    • Rheumatology is consulted 6:11
    • Decreased sensation in toes occurs between strokes 7:14
    • What’s going on with this patient? 8:36
    • What additional labs can we perform? 9:36
    • We spin the urine 11:10
    • What kind of vasculitis are Sjogren’s and lymphoma associated with? 12:22
    • C3 and C4 had already been performed 13:00
    • An overall picture of this patient 13:54
    • What about the strokes? 14:19
    • Should we do more imaging? 15:57
    • At this point we can make a clinical decision 16:33
    • Why make a decision so quickly vs. waiting for biopsy? 18:18
    • Two things you must check before moving forward with a cryoglobulinemic vasculitis 19:46
    • Spoiler alert: The patient is doing really well 20:16

Brought to you by GSK. Considering a treatment change for patients with active SLE? Learn about a treatment option for your patients at treatfortodayandtomorrow.com.

  • What is cryoglobulinemic vasculitis? 21:00
  • What are these immunoglobulins? There are three types of cryoglobulins 22:55
  • Usually driven by another identifiable disease 25:18
  • What is making these immunoglobulins? 26:49
  • We don’t know why these immunoglobulins behave this way 27:18
  • How do you explain the kidneys? 28:28
  • What’s occurring at the tissue level? 29:35
  • How does type 1 present? 30:50
  • Type 2 and type 3 31:12
  • What other organ systems are involved? 33:11
  • I hope you enjoyed this patient presentation 36:00
  • What we’ll discuss in episodes 2 and 3 36:05
  • Thanks for listening 38:03

**Coming soon from Healio, Unmasking COVID-19, a podcast hosted by Gitanjali Pai, MD, infectious disease physician at Memorial Hospital and Physicians’ Clinic in Stilwell, Oklahoma. In this timely new show, Dr. Pai will explore COVID-19’s impact on vulnerable patient populations by answering questions from experts in various medical fields, including oncology, endocrinology and rheumatology. To submit your question for Dr. Pai, email covid19podcast@healio.com.**

We’d love to hear from you! Send your comments/questions to rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum @LCalabreseDO @CCalabreseDO

Disclosure: Brown reports no relevant financial disclosures.

References:

Fuentes A, et al. Current Rheumatology Reports. 2019;21:60.

Silva F, et al. J Autoimmun. 2019;105:102313.

  continue reading

86 episodes

Artwork
iconPartager
 
Manage episode 407440420 series 3560282
Contenu fourni par Healio, Adam J. Brown, and MD. Tout le contenu du podcast, y compris les épisodes, les graphiques et les descriptions de podcast, est téléchargé et fourni directement par Healio, Adam J. Brown, and MD ou son partenaire de plateforme de podcast. Si vous pensez que quelqu'un utilise votre œuvre protégée sans votre autorisation, vous pouvez suivre le processus décrit ici https://fr.player.fm/legal.

Try your hand at this medical mystery, which is followed by some didactics on a fascinating disease which will hopefully make sense of this inscrutable title.

Brought to you by GSK. Consider the long-term impact of disease activity, flares and corticosteroid use on patients with active SLE. Learn more now at treatfortodayandtomorrow.com

  • Intro :22
  • What to expect in each episode :30
  • The case: A 75-year-old man with Sjogren’s and MALT lymphoma presents with recurrent cerebral infarcts of multiple territories 1:10
    • Rheumatology is consulted 6:11
    • Decreased sensation in toes occurs between strokes 7:14
    • What’s going on with this patient? 8:36
    • What additional labs can we perform? 9:36
    • We spin the urine 11:10
    • What kind of vasculitis are Sjogren’s and lymphoma associated with? 12:22
    • C3 and C4 had already been performed 13:00
    • An overall picture of this patient 13:54
    • What about the strokes? 14:19
    • Should we do more imaging? 15:57
    • At this point we can make a clinical decision 16:33
    • Why make a decision so quickly vs. waiting for biopsy? 18:18
    • Two things you must check before moving forward with a cryoglobulinemic vasculitis 19:46
    • Spoiler alert: The patient is doing really well 20:16

Brought to you by GSK. Considering a treatment change for patients with active SLE? Learn about a treatment option for your patients at treatfortodayandtomorrow.com.

  • What is cryoglobulinemic vasculitis? 21:00
  • What are these immunoglobulins? There are three types of cryoglobulins 22:55
  • Usually driven by another identifiable disease 25:18
  • What is making these immunoglobulins? 26:49
  • We don’t know why these immunoglobulins behave this way 27:18
  • How do you explain the kidneys? 28:28
  • What’s occurring at the tissue level? 29:35
  • How does type 1 present? 30:50
  • Type 2 and type 3 31:12
  • What other organ systems are involved? 33:11
  • I hope you enjoyed this patient presentation 36:00
  • What we’ll discuss in episodes 2 and 3 36:05
  • Thanks for listening 38:03

**Coming soon from Healio, Unmasking COVID-19, a podcast hosted by Gitanjali Pai, MD, infectious disease physician at Memorial Hospital and Physicians’ Clinic in Stilwell, Oklahoma. In this timely new show, Dr. Pai will explore COVID-19’s impact on vulnerable patient populations by answering questions from experts in various medical fields, including oncology, endocrinology and rheumatology. To submit your question for Dr. Pai, email covid19podcast@healio.com.**

We’d love to hear from you! Send your comments/questions to rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum @LCalabreseDO @CCalabreseDO

Disclosure: Brown reports no relevant financial disclosures.

References:

Fuentes A, et al. Current Rheumatology Reports. 2019;21:60.

Silva F, et al. J Autoimmun. 2019;105:102313.

  continue reading

86 episodes

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