084: Vascular dysfunction and Multiple Sclerosis. How Your vessels Could Shape Your MS Journey with Dr. Jonathan Pansieri

MS-Perspektive - The Multiple Sclerosis Podcast

Dr. Jonathan Pansieri explains how vascular dysfunction could worsen multiple sclerosis and become a target for future treatment approaches.

You can read all questions and answers here: https://ms-perspektive.com/84-Vascular-dysfunction

When it comes to multiple sclerosis (MS), you probably know that the immune system plays a role in attacking the nervous system. But what if your blood vessels also played an important role? In this interview, we dive into the fascinating link between vascular dysfunction and MS with insights from Dr. Jonathan Pansieri. From how the blood-brain barrier is disrupted, to how impaired blood flow can worsen inflammation, we explore how vascular issues could be affecting your journey with MS. Understanding this link could open new doors on treatment strategies and offer fresh hope to patients living with this complex disease.

Table of Contents

• Introduction – Who is Dr. Jonathan Pansieri?
• Vascular dysfunction Impact on MS
• The Role of Microglia in MS
• Potential Applications of Genetic Research
• MS, Dementia, and Alzheimer's
• Quickfire Q&A Session
• Farewell

Introduction – Who is Dr. Jonathan Pansieri?

I am Dr Jonathan Pansieri, neuroscientist in the Medical Science Division of the University of Oxford, and a fellow from the UK-MS society. I am 36 years-old, living with my partner who is also a scientist in the Department of Surgery focusing on prostate cancer. I am a dog person, so I would love to have 2 big dogs in the near future, but I will need to adapt my schedule for that! If there is something else to say about me, as a French citizen, I miss so much the lovely French pastries that I’m trying to make my own croissant and pain au chocolat, but despite 5 years of training now, I definitely need to improve my skills, it is such a disaster so far…

How and where can interested people follow your research activities?

As an academic, I’m always dedicated to share our progresses with both the research community and individuals living with progressive MS. In addition, we regularly host patient information days in Oxford to present the latest in clinical care, symptom management, and research advancements, so stay tune!

You can also follow my work on Twitter (@group_deluca and @JPansieri), where I share insights and updates (though I wish I could share more!). Additionally, you can connect with me on ResearchGate (https://www.researchgate.net/profile/Jonathan-Pansieri) and LinkedIn (https://www.linkedin.com/in/jonathan-pansieri-11887bb5/), where I’m always open to discussions. Thank you all for your support—let’s keep pushing forward together!

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Many thanks to Jonathan for the exciting interview and also to all his colleagues working on the project. It sounds very promising.

See you soon and try to make the best out of your life, Nele

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