The Science of Longevity with Dr Tommy Wood

Metagenics Institute Podcast

Dr Tommy Wood earned his medical degree at the University of Oxford, and subsequently completed PhD in physiology and neuroscience at the University of Oslo. Currently, he holds academic positions at the University of Washington and Institute for Human and Machine Cognition. One of Dr Wood’s research interests is developing easily-accessible methods with which to track human health, performance, and longevity. In this episode, Dr Wood shares a plethora of information regarding the science of longevity, including patterns in ageing, determining biological age, and importantly, whether specific ingredients can increase longevity.

*Highlights *

• The fascination with extending the lifespan (5:00)
• Looking to the Blue Zones (8:30)
• The biomarkers of ageing (15:50)
• Determining your biological age (21:00)
• Biological drivers of ageing (31:40)
• Diving into caloric restriction (38:00)
• Macronutrients for health and longevity (55:00)
• Ingredients to improve longevity (75:00)

Useful links and resources: e.g:
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Genetic testing providers Tommy Wood mentions:
Elysium - https://www.elysiumhealth.com/en-us/index
Chronomics - https://www.chronomics.com/dna

Paper – Li J, Bonkowski MS, Moniot S, Zhang D, Hubbard BP, Ling AJ, Rajman LA, Qin B, Lou Z, Gorbunova V, Aravind L, Steegborn C, Sinclair DA. A conserved NAD+ binding pocket that regulates protein-protein interactions during aging. Science. 2017 Mar 24;355(6331):1312-1317. doi: 10.1126/science.aad8242. PMID: 28336669

Link: https://pubmed.ncbi.nlm.nih.gov/28336669/
Paper – Newman S. Supercentenarians and the oldest old are concentrated into regions with no birth certificates and short lifespans. 2019 Jul. doi: 10.1101/704080

Link - https://www.researchgate.net/publication/334497888_Supercentenarians_and_the_oldest-old_are_concentrated_into_regions_with_no_birth_certificates_and_short_lifespans