CD8+ T-cell Differentiation And Treatment Response In AML; ATM Germline Pathogenic Variants Affect Cancer Outcomes In Ataxia-telangiectasia; Efficacy Of A Selective Menin-KMT2A Inhibitor In KMT2A- And NPM1-altered Leukemias Blood podcast

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CD8+ T-cell differentiation and treatment response in AML; ATM germline pathogenic variants affect cancer outcomes in ataxia-telangiectasia; efficacy of a selective menin-KMT2A inhibitor in KMT2A- and NPM1-altered leukemias

5d ago 22:42

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In this week's episode we’ll discuss how CD8+ T-cell differentiation and dysfunction inform treatment response in acute myeloid leukemia; learn more about the effect of ATM germline pathogenic variants on the outcomes in children with ataxia-telangiectasia and hematological malignancies; and discuss the preclinical efficacy of a potent, selective menin-KMT2A inhibitor JNJ-75276617 in KMT2A- and NPM1-altered leukemias.

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