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Episode 17. Acquired Aplastic Anemia
Manage episode 357338269 series 3369804
Contenu fourni par Rajshekhar Chakraborty and Ashwin Kishtagari, Rajshekhar Chakraborty, Ashwin Kishtagari, and Edward Cliff. Tout le contenu du podcast, y compris les épisodes, les graphiques et les descriptions de podcast, est téléchargé et fourni directement par Rajshekhar Chakraborty and Ashwin Kishtagari, Rajshekhar Chakraborty, Ashwin Kishtagari, and Edward Cliff ou son partenaire de plateforme de podcast. Si vous pensez que quelqu'un utilise votre œuvre protégée sans votre autorisation, vous pouvez suivre le processus décrit ici https://fr.player.fm/legal.
In this episode, we discuss the management of acquired aplastic anemia with Dr. Amy DeZern. Here are the links to some of the key articles discussed in this show:
1. Review article on aplastic anemia:
https://www.nejm.org/doi/10.1056/NEJMra1413485
2. RCTs testing whether addition of cyclosporine to ATG improves outcomes in aplastic anemia:
https://www.nejm.org/doi/10.1056/NEJM199105093241901
https://www.sciencedirect.com/science/article/pii/S0006497120489748
3. RCT testing horse versus rabbit ATG in aplastic anemia:
https://www.nejm.org/doi/full/10.1056/nejmoa1103975
4. Single-arm study of eltrombopag in addition to standard immunosuppressive therapy in aplastic anemia:
https://www.nejm.org/doi/10.1056/NEJMoa1613878
5. Long-term follow up of patients treated with immunosuppressive therapy and eltrombopag:
https://ashpublications.org/blood/article/139/1/34/476916
6. RACE Trial: Standard immunosuppressive therapy +/- eltrombopag in aplastic anemia:
https://www.nejm.org/doi/10.1056/NEJMoa2109965
7. Clinical and molecular determinants of clonal evolution in patients with aplastic anemia:
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