Get ready—Season 6 of Unseen Upside launches October 21. This season, we’re taking you behind the scenes to explore how AI is transforming our world. From labs and classrooms to clinics and fields, we’ll follow the capital and uncover how AI is driving the next chapter of human progress. Tune in for episode one on your favorite podcast platform, Tuesday, October 21.…
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Contenu fourni par Healio. Tout le contenu du podcast, y compris les épisodes, les graphiques et les descriptions de podcast, est téléchargé et fourni directement par Healio ou son partenaire de plateforme de podcast. Si vous pensez que quelqu'un utilise votre œuvre protégée sans votre autorisation, vous pouvez suivre le processus décrit ici https://fr.player.fm/legal.
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1 Lung Cancer Edition: Top Headlines for Week of October 13, 2025 13:23
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, radiation is a ‘strong alternative’ for surgery, FDA approves combination therapy for small cell lung cancer and more. Read the full coverage here: Radiation a ‘strong alternative’ to surgery for early-stage lung cancer FDA approves lurbinectedin, atezolizumab combination for small cell lung cancer Diagnostic yield high with robotic-assisted bronchoscopy in peripheral lung lesions Machine learning model predicts urgent care visits during lung cancer treatment Evidence is ‘clear’: Medicaid expansion significantly improves long-term cancer survival References: Gonzalez BD, et al. JCO Clin Cancer Inform . 2025;doi:10.1200/CCI-24-00315 . Kleber T, et al. Abstract 268. Presented at: ASTRO Annual Meeting; Sept. 27-Oct. 1, 2025; San Francisco. Press Release Schafer EJ, et al. Cancer Discov . 2025;doi:10.1158/2159-8290.CD-25-1244. Steinack C, et al. OA1178: Robotic-assisted bronchoscopy with integrated cone-beam CT vs. conventional bronchoscopy for diagnosing peripheral pulmonary lesions: An open-label randomized controlled trial. Presented at: European Respiratory Society International Congress; Sept. 27-Oct. 1, 2025; Amsterdam.…
1 Healio Minute Podcast, Orthopedics Edition: Top Headlines for Week of October 15, 2025 11:22
11:22 Lire Plus Tard Lire Plus Tard Des listes J'aime Aimé11:22
Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, bioinductive implants for ACL reconstruction, osteochondral defects treatments and more. Read the full coverage here: ACL reconstruction with reinforced bioinductive implant may yield favorable outcomes Multiplug, single-plug techniques had comparable outcomes for osteochondral defects MRI-based clinical prediction model identified risk factors for patellar instability New technology, cost strategies continue to move robotic-assisted surgery forward Physician referral to physical therapy underutilized for patients with knee osteoarthritis References: Healio Interviews Khoja SS, et al. Arthritis Care Res . 2025;doi:10.1002/acr.25630. McMillan S, et al. Surg Technol Int . 2025;doi:10.52198/25.STI.45.OS1888. Mufti YN, et al. Am J Sports Med . 2025;doi:10.1177/03635465251352172. Nukala V, et al. Arthrosc Sports Med Rehabil . 2025;doi:10.1016/j.asmr.2025.101159.…
1 Healio Minute Podcast, Orthopedics Edition: Top Headlines for Week of September 30, 2025 18:07
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, we look at AI bias, nonsurgical biologic therapies and more. Read the full coverage here: ‘Math, not magic’: Identify and combat bias in AI Orthobiologics: Commit to evidence-based practice, foster cautious optimism TJR indications expand, making it a young man’s game Successful management of PJI occurred in about 50% of patients Risks of anteromedial tibial tubercle transfer are minimal and the benefits great References: Expert Submission Healio Interviews Higuera Rueda C, et al. Paper 1409. Presented at: Musculoskeletal Infection Society Annual Meeting; Aug. 1-2, 2025; Jersey City, N.J. Engagement Time: 18 minutes…
1 Lung Cancer Edition: Top Headlines for Week of September 22, 2025 13:10
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, FDA approves subcutaneous chemotherapy for solid tumors, improvements to shared decision-making and more. Read the full coverage here: FDA approves Hernexeos as first oral therapy for NSCLC with HER2 mutations Communication, knowledge critical to improve shared decision-making for lung cancer Detection of ctDNA could help determine use of immunotherapy for small cell lung cancer Subcutaneous amivantamab plus lazertinib produces similar results to IV regimen in NSCLC Lung cancer screening guidance needed for certain never-smokers References: Bi N, et al. Abstract 2034. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona. Press Release Scott SC, et al. Abstract 1798. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona. Shum E, et al. Abstract 2172. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona. Villalon D, et al. Abstract 2368. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona.…
1 Gastroenterology Edition: Top Headlines for Week of September 15, 2025 11:47
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, ultra-processed grains linked to elevated risk for IBD, CTA use for GI bleeds increase and more. Read the full coverage here: Ultra-processed grains linked to elevated risk for IBD, especially ulcerative colitis ‘Double whammy:’ CTA use for GI bleeds rise, but diagnostic yield drops ‘Another layer of benefit’: GLP-1s linked to lower risk for peptic ulcer disease ‘Simplified care models’ needed for chronic HBV care to meet 2030 global elimination goals ‘Stay vigilant’: Routine exposure to AI may reduce ADR in standard colonoscopy References: Budzyń K, et al. Lancet Gastroenterol Hepatol. 2025;doi:10.1016/S2468-1253 (25) 00133-5. Narula N, et al. Am J Gastro . 2025;doi:10.14309/ajg.0000000000003700 . Prasad S, et al. JAMA Netw Open. 2025;doi:10.1001/jamanetworkopen.2025.29746 . Seika P, et al. Clin Gastroenterol Hepatol. 2025;doi:10.1016/j.cgh.2025.08.015 . Stockdale AJ, et al. Lancet Gastroenterol Hepatol . 2025;doi:10.1016/S2468-1253(25)00163-3.…
1 Orthopedics Edition: Top Headlines for Week of September 15, 2025 13:05
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, we look at labral reconstruction in adolescents, the risk of skipping breakfast on osteoporotic fractures and more. Read the full coverage here: Labral reconstruction yielded favorable outcomes among adolescent patients Skipping breakfast, eating late dinners may raise risk for major osteoporotic fractures AI may personalize patient care, identify surgical risks Surgical fixation for pickleball-related Achilles ruptures may improve quality of life Screening for osteoporosis, preventing fractures essential in diabetes care References: Chen C, et al. Paper 17. Presented at: American Orthopaedic Society for Sports Medicine Annual Meeting; July 10-12, 2025; Nashville, Tenn Domb BG, et al. Paper 50. Presented at: American Orthopaedic Society for Sports Medicine Annual Meeting; July 10-12, 2025; Nashville, Tenn. Kemmis K. Presentation D27. Presented at: ADCES25; Aug. 8-11, 2025; Phoenix. Nakajima H, et al. J Endocr Soc. 2025;doi:10.1210/jendso/bvaf127. Weight C. AI in the OR: Personalizing care, lowering complications and automating surgery. Presented at: Cleveland Clinic’s A.I. Summit for Healthcare Professionals; July 11, 2025; Cleveland.…
1 Orthopedics Edition: Top Headlines for Week of August 25, 2025 11:18
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, we look at the risk orthopedic surgeons face from insufficient malpractice coverage, the role of AI in osteoporosis and more. Read the full coverage here: AI-assisted diagnostic system may identify osteopenia, osteoporosis Insufficient malpractice coverage may place surgeons caring for elite athletes at risk Psychological readiness, stress improved 2 years after ACL reconstruction Patella resurfacing reduced maltracking, had comparable outcomes as nonresurfacing Patellofemoral osteochondral allograft transplantation may effectively treat lesions References: Jolissaint JE, et al. Paper 1538. Presented at: Musculoskeletal Infection Society Annual Meeting; Aug. 1-2, 2025; Jersey City, N.J. Milewski MD, et al. Paper 57. Presented at: American Orthopaedic Society for Sports Medicine Annual Meeting; July 10-12, 2025; Nashville, Tenn. Moro T, et al. J Orthop Res. 2025;doi:10.1002/jor.70000. Ramkumar PN, et al. Paper 37. Presented at: American Orthopaedic Society for Sports Medicine Annual Meeting; July 10-13, 2025; Nashville, Tenn. Wang T, et al. Paper 28. Presented at: American Orthopaedic Society for Sports Medicine Annual Meeting; July 10-12, 2025; Nashville, Tenn.…
1 Lung Cancer Edition: Top Headlines for Week of August 18, 2025 11:53
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, FDA approves first oral therapy for NSCLC, interstitial lung disease diagnosis raises risk for lung cancer and more. Read the full coverage here: FDA approves Hernexeos as first oral therapy for NSCLC with HER2 mutations ILD diagnosis raises risk for lung cancer Uninsured patients benefit less from immune checkpoint inhibitors than privately insured Shared decision-making visit improves annual lung cancer screening adherence Indoor tobacco, e-cigarette use more common in rural vs. urban homes References: Chung Y, et al. CHEST . 2025;doi:10.1016/j.chest.2025.06.026. Press Release Steinberg AW, et al. Ann Am Thorac Soc . 2025;doi:10.1513/AnnalsATS.202504-419OC. Xu H, et al. JAMA Netw Open . 2025;doi:10.1001/jamanetworkopen.2025.19630. Zhao J, et al. JAMA Netw Open . 2025;doi:10.1001/jamanetworkopen.2025.19274 .…
1 Gastroenterology Edition: Top Headlines for Week of August 18, 2025 11:38
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, opioid deaths with GI issues tripled in the past decade, prophylactic vancomycin may reduce risk for recurrent C. difficile and more. Read the full coverage here: ‘Deeply alarming’: Opioid deaths with GI issues tripled in the past decade Prophylactic vancomycin may reduce risk for recurrent C. difficile CRC disparities in Black communities stem from access, not biology, experts say Mediterranean, plant-based diets linked to lower risk for chronic constipation Psychiatric disorders ‘common’ among patients with inflammatory bowel disease References: Appiah JK, et al. Cureus . 2025;doi:10.7759/cureus.86489. Cadogan K, et al. Crohns Colitis 360. 2025;doi:10.1093/crocol/otaf035. Keating JA, et al. JAMA Netw Open. 2025;doi:10.1001/jamanetworkopen.2025.17834 . May FP, et al. Nat Rev Gastroenterol Hepatol . 2025;doi: 10.1038/s41575-025-01087-3 . Wang Y, et al. Gastroenterology . 2025;doi:10.1053/j.gastro.2025.06.020 .…
1 Orthopedics Edition: Top Headlines for Week of August 11, 2025 16:04
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, we look at how state opioid cap laws impact total joint replacements, how nutrition affects orthopedic surgery and more. Read the full coverage here: State opioid cap laws may reduce opioid fills after total joint replacement Nutrition may be key to muscle, bone health after surgery Should malnutrition screening occur before orthopedic surgery? Pyrocarbon hemiarthroplasty with glenoid reaming may improve outcomes for young patients Physicians under pressure in name, image and likeness era References: Expert Submission Healio Interviews Healio Interviews Ranieri R, et al. J Shoulder Elbow Surg . 2025;doi:10.1016/j.jse.2024.06.028. Thirukumaran CP, et al. JAMA Netw Open . 2025;doi:10.1001/jamanetworkopen.2025.4448.…
In this edition, we look at how testosterone and exercise affect older women with hip fracture, how vitamin C may be an effective alternative to glucocorticoids and more. Read the full coverage here: Function not improved with testosterone plus exercise after hip fracture in older women Vitamin C may be effective alternative to glucocorticoids in total hip arthroplasty Hip resurfacing may be effective for younger, active men with osteoarthritis Robotic-assisted THA may reduce opioid requirements vs. manual, computer-assisted THA One-stage exchange may provide alternative for chronic PJI References: Binder EF, et al. JAMA Netw Open . 2025;doi:10.1001/jamanetworkopen.2025.10512. Expert Submission Giannakis P, et al. e-Poster 6833. Presented at: Anesthesiology and Acute Pain Medicine Meeting; May 1-3, 2025; Orlando. Jiang W, et al. J Bone Joint Surg Am . 2025;doi:10.2106/JBJS.24.01080. Zuke WA, et al. J Bone Joint Surg Am . 2025;doi:10.2106/JBJS.24.00926.…
1 Lung Cancer Edition: Top Headlines for Week of July 21, 2025 11:24
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, light physical activity linked to lower cancer risk, lung lesion diagnostic yield from bronchoscopy and more. Read the full coverage here: ‘Every bit of movement counts’: Even light physical activity linked to lower cancer risk Robotic, electromagnetic navigation bronchoscopy have similar lung lesion diagnostic yield Women with history of adverse pregnancy outcomes face elevated risk for future COPD Long-term blood pressure lowering does not appear to impact risk for new-onset cancer Most patients with advanced cancer do not undergo next-generation sequencing testing References: Chehade CH, et al. Abstract 11014. Presented at: ASCO Annual Meeting; May 30-June 3, 2025; Chicago. Paez R, et al. Am J Respir Crit Care Med . 2025;doi:10.1164/rccm.202409-1846OC. Shreves AH, et al. Br J Sports Med. 2025;doi:10.1136/bjsports-2024-109360 . Sridhar S, et al. Adverse pregnancy outcomes and future maternal risk of developing COPD: An analysis of the Women’s Health Initiative. Presented at: American Thoracic Society International Conference; May 16-21, 2025; San Francisco. Zazarzadeh M, et al. JACC CardioOncol . 2025;doi:10.1016/j.jaccao.2025.03.005.…
1 Gastroenterology Edition: Top Headlines for Week of July 14, 2025 12:50
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, IBD social risks linked to unplanned ED use, anal cancer screening for men with HIV may cut deaths by 65% and more. Read the full coverage here: Nearly two-thirds of adults with IBD experience social risks linked to unplanned ED use Anal cancer screening at age 35 for gay, bisexual men with HIV may cut deaths by 65% ‘Not just a physical issue’: CRC linked to adverse sexual health outcomes among women ‘We need to take ownership’: ACG guideline urges preventive care in IBD management Managing gut dysbiosis may offer ‘therapeutic window’ for severe alcoholic hepatitis References: Deshmukh AA, et al. Ann Intern Med. 2025;doi:10.7326/ANNALS-24-01426 . Farraye FA, et al. Am J Gastroenterol. 2025;doi:10.14309/ajg.0000000000003541. Kim S, et al. Clin Gastroenterol Hepatol. 2025;doi:10.1016/j.cgh.2025.03.031 . Oveisi N, et al. J Natl Cancer Inst. 2025;doi:10.1093/jnci/djaf120 . Vaithiyam V, et al. Cureus. 2025;doi:10.7759/cureus.85516 .…
In this edition, we look at knee replacement survivorship, how DEI statements may lead to more women in sports medicine programs and more. Read the full coverage here: Public DEI statements may lead to more women faculty, fellows in sports medicine programs Knee replacements have high long-term survivorship in young patients Aragonite-based scaffold yielded similar outcomes between men, women with chondral defects Platelet-rich plasma may be inferior to corticosteroid injections for knee osteoarthritis Bioinductive collagen implant had similar outcomes as suture anchors in rotator cuff tears References: Hurley ET, et al. Clinical outcomes of bioinductive collagen implants for high-grade partial rotator cuff tears. Presented at: Arthroscopy Association of North America Annual Meeting; May 8-10, 2025; Washington, D.C Kon E, et al. Female patients report comparable results to males after the implantation of an aragonite scaffold. Presented at: Arthroscopy Association of North America Annual Meeting; May 8-10, 2025; Washington, D.C. Pai J, et al. Diversity, equity and inclusion initiatives and faculty roles in orthopedic sports fellowship. Presented at: Arthroscopy Association of North America Annual Meeting; May 8-10, 2025; Washington, D.C. Swartz GN, et al. Poster e251. Presented at: American Academy of Orthopaedic Surgeons Annual Meeting; March 10-14, 2025; San Diego. Weinblatt AI, et al. Paper 416. Presented at: American Academy of Orthopaedic Surgeons Annual Meeting; March 10-14, 2025; San Diego.…
1 Lung Cancer Edition: Top Headlines for Week of June 23, 2025 13:59
13:59 Lire Plus Tard Lire Plus Tard Des listes J'aime Aimé13:59
Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, DREAM program ‘better than anything’ available, maintenance regimen a potential new standard and more. Read the full coverage here: DREAM program ‘better than anything’ available for patients with advanced lung cancer Maintenance regimen a potential new standard in extensive-stage small cell lung cancer ‘It can save their lives’: Annual lung cancer screening improves cancer detection rate Assay predicts adjuvant chemotherapy benefit in early-stage non-small cell lung cancer High environmental burden has associations with incidence of multiple cancer types References: Kamarei AMA, et al. Abstract 11009. Presented at: ASCO Annual Meeting; May 30-June 3, 2025; Chicago. Kim RY, et al. JAMA Netw Open . 2025;doi:10.1001/jamanetworkopen.2025.0942. Paz-Ares LG, et al. Abstract #8006. Presented at: ASCO Annual Meeting; May 30-June 3, 2025; Chicago. Press Release Spigel DR, et al. Abstract LBA8027. Presented at: ASCO Annual Meeting; May 30-June 3, 2025; Chicago.…
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1 Lung Cancer Edition: Top Headlines for Week of June 2, 2025 13:41
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, reduction efforts prevent 3.8 million lung cancer deaths since 1970, first-line combination should be ‘new standard’ in advanced lung cancer and more. Read the full coverage here: Smoking cessation, reduction efforts prevent 3.8 million lung cancer deaths since 1970 First-line combination should be ‘new standard’ in advanced lung cancer Only 1 in 5 people treated with immune checkpoint inhibitors respond to therapy ‘It can save their lives’: Annual lung cancer screening improves cancer detection rate ‘Are we giving false hope?’: Few hospitalized people with cancer benefit from immunotherapy References: Haslam A, et al. Int J Cancer . 2025;doi:10.1002/ijc.35347 . Islami F, et al. CA Cancer J Clin . 2025;doi:10.3322/caac.70005 . Kim RY, et al. JAMA Netw Open . 2025;doi:10.1001/jamanetworkopen.2025.0942. Riaz F, et al. JCO Oncol Pract. 2025;doi:10.1200/OP-24-00788 . Yang JCH, et al. Amivantamab plus lazertinib vs osimertinib in first-line EGFR -mutant advanced NSCLC. Presented at: European Lung Cancer Congress; March 26-29, 2025; Paris.…
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1 Lung Cancer Edition: Top Headlines for Week of April 28, 2025 13:59
13:59 Lire Plus Tard Lire Plus Tard Des listes J'aime Aimé13:59
Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, reduction efforts prevent 3.8 million lung cancer deaths since 1970, first-line combination should be ‘new standard’ in advanced lung cancer and more. Read the full coverage here: Smoking cessation, reduction efforts prevent 3.8 million lung cancer deaths since 1970 First-line combination should be ‘new standard’ in advanced lung cancer Only 1 in 5 people treated with immune checkpoint inhibitors respond to therapy ‘It can save their lives’: Annual lung cancer screening improves cancer detection rate ‘Are we giving false hope?’: Few hospitalized people with cancer benefit from immunotherapy References: Haslam A, et al. Int J Cancer . 2025;doi:10.1002/ijc.35347 . Islami F, et al. CA Cancer J Clin . 2025;doi:10.3322/caac.70005 . Kim RY, et al. JAMA Netw Open . 2025;doi:10.1001/jamanetworkopen.2025.0942. Riaz F, et al. JCO Oncol Pract. 2025;doi:10.1200/OP-24-00788 . Yang JCH, et al. Amivantamab plus lazertinib vs osimertinib in first-line EGFR -mutant advanced NSCLC. Presented at: European Lung Cancer Congress; March 26-29, 2025; Paris.…
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1 Gastroenterology Edition: Top Headlines for Week of April 14, 2025 12:01
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, sick food service workers top driver of viral foodborne outbreaks in US, no weight loss benefit with semaglutide before bariatric surgery and more. Read the full coverage here: Sick food service workers remain top driver of viral foodborne outbreaks in US ‘We have work to do’: No weight loss benefit with semaglutide before bariatric surgery Mailed FIT outreach program boosts colorectal cancer screening in rural areas ‘Distinct viral exposure patterns’ found in patients with Crohn’s years before diagnosis Mortality, dropout risk higher on liver transplant waitlist in low-density areas References: Coronado GD, et al. JAMA Netw Open. 2025;doi:10.1001/jamanetworkopen.2025.0928 . Holst MM, et al. MMWR Surveill Summ. 2025;doi:10.15585/mmwr.ss7401a1. Mathur V, et al. JAMA Surg. 2025;doi:10.1001/jamasurg.2025.0001 . Nandy A, et al. Gastroenterology. 2025;doi:10.1053/j.gastro.2025.01.247 Tanaka T, et al. JAMA Netw Open. 2025;doi:10.1001/jamanetworkopen.2025.1759 .…
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1 Lung Cancer Edition: Top Headlines for Week of March 17, 2025 12:20
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, recurrence-free survival estimates in less advanced lung cancer, bronchoscopy-guided microwave ablation safe in lung abnormality and more. Read the full coverage here: Recurrence-free survival estimates after surgery higher in less advanced lung cancer Electromagnetic navigation bronchoscopy-guided microwave ablation safe in lung abnormality High prevalence of atherosclerosis detected in patients entering lung cancer therapy Wood dust exposure negatively impacts lung function in carpenters 40% of people treated with chemotherapy develop persistent, severe nerve pain References: D'Souza RS, et al. Reg Anesth Pain Med . 2025;doi:10.1136/rapm-2024-106229 . Elfatih NM, et al. BMC Pulm Med. 2025;doi:10.1186/s12890-025-03535-x. Malozzi C. Implementation science (application of research into practice/policy). Presented at: American College of Cardiology’s Advancing the Cardiovascular Care of the Oncology Patient course; Feb. 14-16, 2025; Washington, D.C. Rajaram R, et al. CHEST. 2023;doi:10.1016/j.chest.2023.11.042. Wang S, et al. J Thorac Dis. 2024;doi:10.21037/jtd-24-1052.…
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1 Lung Cancer Edition: Top Headlines for Week of February 17, 2025 13:36
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, robotic-assisted bronchoscopy a ‘game changer’, global mortality related to tobacco drops, particulate matter rises and more. Read the full coverage here: Robotic-assisted bronchoscopy a ‘game changer’ in early diagnosis of lung cancer Global lung cancer mortality related to tobacco drops, particulate matter rises in 2019 Osimertinib linked to more therapy-related cardiac events than other TKIs for NSCLC Survival better with lobectomy vs. wedge resection in early stage lung cancer Zenocutuzumab exhibits efficacy in NRG1 fusion-positive cancers References: Expert Submission Jani CT, et al. eClinicalMedicine. 2025;doi:10.1016/j.eclinm.2024.103033. Lin CY, et al. JAMA Netw Open . 2024;doi:10.1001/jamanetworkopen.2024.48364. Schram AM, et al. N Engl J Med. 2025;doi:10.1056/NEJMoa2405008 . Seder C. Anatomic lung resection is associated with improved survival compared with wedge resection for stage IA non-small cell lung cancer. Presented at: 2025 Society of Thoracic Surgeons Annual Meeting; Jan. 24-26; Los Angeles.…
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1 Lung Cancer Edition: Top Headlines for Week of January 20, 2025 11:23
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, combination extends survival vs. standard first-line therapy, integrated care for smoking cessation during lung cancer screening and more. Read the full coverage here: Combination extends survival vs. standard first-line therapy for advanced lung cancer Integrated care ‘best treatment option’ for smoking cessation during lung cancer screening FDA proposes cap on nicotine levels in cigarettes Global lifetime risk for lung cancer in 2022 differs by human development index, sex FDA grants priority review to oral non-small cell lung cancer drug References: Cinciripini P, et al. JAMA Intern Med . 2024;doi:10.1001/jamainternmed.2024.7288. Li M, et al. Chin Med J (Engl). 2024;doi:10.1097/CM9.0000000000003368. Press Release Press Release Press Release…
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1 Lung Cancer Edition: Top Headlines for Week of December 16, 2024 13:25
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, we bring you Healio’s top lung cancer headlines in 2024. Read the full coverage here: California doctor with lung cancer receives first-of-its-kind lung-liver transplant ‘We were shocked’: Vaping considerably increases lung cancer risk among people who smoke FDA places hold on trial of cell therapy for lung cancer after patient death Findings highlight ‘desperate need’ to improve end-of-life cancer treatment ‘We have the technology’: Telehealth increases access to palliative care for cancer References: Canavan ME, et al. JAMA Oncol . 2024;doi:10.1001/jamaoncol.2024.1129. Greer JA, et al. Abstract LBA3. Presented at: ASCO Annual Meeting; May 31-June 4, 2024: Chicago. Healio Interviews Press Release Press Release…
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1 Lung Cancer Edition: Top Headlines for Week of November 11, 2024 10:57
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, single-fraction SBRT outcomes for central lung tumors, adjuvant durvalumab extends survival in limited-stage small cell lung cancer and more. Read the full coverage here: Single-fraction SBRT confers ‘surprisingly excellent’ outcomes for central lung tumors Adjuvant durvalumab extends survival in limited-stage small cell lung cancer Depression among people with head and neck cancers likely underreported, undertreated FDA approves tumor treating fields as part of combination therapy for advanced lung cancer First-line maintenance regimen improves OS, PFS in extensive-stage small cell lung cancer References: Cheng Y, et al. Abstract LBA81. Presented at: European Society for Medical Oncology Congress; Sept. 13-17, 2024; Barcelona, Spain. Malik NK, et al. Abstract 285. Presented at: ASTRO Annual Meeting; Sept. 29-Oct. 2, 2024; Washington, D.C. Martinez MC, et al. JAMA Otolaryngol Head Neck Surg . 2024;doi:10.1001/jamaoto.2024.3233 . Press Release Press Release…
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1 Lung Cancer Edition: Top Headlines for Week of October 14, 2024 10:45
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, FDA approves Rybrevant for advanced lung cancer, screening orders in eligible patients higher with digital health program and more. Read the full coverage here: FDA approves Rybrevant for advanced lung cancer Lung cancer screening orders in eligible patients higher with digital health program FDA approves Opdivo regimen for resectable NSCLC Study quantifies survival benefit of immunotherapy in metastatic NSCLC FDA expands osimertinib approval for advanced non-small cell lung cancer References: Miller DP, et al. A direct-to-patient digital health program increases lung cancer screening: A pragmatic randomized controlled trial of mPATH-Lung. Presented at: CHEST Annual Meeting; Oct. 6-9, 2024; Boston . Press Release Press Release Press Release Ward Y, et al. Cancer. 2024;doi:10.1002/cncr.35476 .…
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Healio Minute
1 Rheumatology/Psoriatic Arthritis Edition: Top Headlines for Week of September 23, 2024 11:48
11:48 Lire Plus Tard Lire Plus Tard Des listes J'aime Aimé11:48
Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, blue-collar workers more likely to miss work or quit due to psoriatic arthritis, infliximab biosimilar increase after release of a third option and more. Read the full coverage here: Blue-collar workers more likely to miss work, quit due to psoriatic arthritis Infliximab biosimilar uptake rapidly increased only after release of a third option National Psoriasis Foundation to honor leaders at 2025 Commit to Cure Gala Safety checklist compiles clinically important DMARD warnings in one place Guselkumab demonstrates long-term efficacy, safety in psoriasis References: Colla N, et al. Clin Rheumatol. 2024;doi:10.1007/s10067-024-07077-1. Gargiulo L, et al. J Drugs Dermatol . 2024;doi:10.36849/JDD.7486R1. Press Release Roberts ET, et al. Arthritis Rheumatol. 2024;doi:10.1002/art.42963. Skaarup L, et al. Drug Saf. 2024;doi:10.1007/s40264-024-01461-1.…
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Healio Minute
1 Lung Cancer Edition: Top Headlines for Week of September 16, 2024 13:55
13:55 Lire Plus Tard Lire Plus Tard Des listes J'aime Aimé13:55
Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, FDA approves first subcutaneous anti-PD-L1 cancer immunotherapy, ivonescimab ‘may be a new standard’ and more. Read the full coverage here: FDA approves first subcutaneous anti-PD-L1 cancer immunotherapy Ivonescimab extends PFS vs. pembrolizumab in advanced NSCLC, may be ‘a new standard’ Perioperative nivolumab improves outcomes in resectable NSCLC Despite progress, barriers to lung cancer biomarker testing persist Atezolizumab regimen ‘merits further study’ for unresectable NSCLC References: Forde PM, et al. Abstract 3589. Presented at: IASLC World Conference on Lung Cancer; Sept. 7-10, 2024; San Diego. Press Release Ross HJ, et al. JAMA Oncol. 2024;doi:10.1001/jamaoncol.2024.1897. Smeltzer M, et al. Abstract 3000. Presented at: IASLC World Conference on Lung Cancer; Sept. 7-10, 2024; San Diego. Zhou C, et al. Abstract 2700. Presented at: IASLC World Conference on Lung Cancer; Sept. 7-10, 2024; San Diego.…
In this edition, enrollment and dosing complete in phase 1 trial of AIV007, popular benchmarks in clinical practice guidelines and more. Read the full coverage here: Enrollment, dosing complete in phase 1 trial of AIV007 for AMD, diabetic macular edema OCT, visual acuity popular benchmarks in clinical practice guidelines for DME First patient dosed in phase 2 trial of EC-104 implant for diabetic macular edema OCS-01 eye drop for DME in second stage of phase 3 trial Q&A: Susvimo delivers immediate durability after implantation in wet AMD References: Crawford C. Update on OCS-01: A novel topical drop for DME in phase 3 trials. Presented at: Clinical Trials at the Summit; June 8, 2024; Park City, Utah. Healio Interviews McAllister M, et al. Assessing the strength of clinical practice guidelines for managing diabetic macular edema — A systematic literature review. Presented at: American Society of Retina Specialists annual meeting; July 17-20, 2024; Stockholm. Press Release Press Release…
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Healio Minute
1 Rheumatology/Psoriatic Arthritis Edition: Top Headlines for Week of August 19, 2024 11:18
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Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, drug discounts through Medicare price negotiations, opioid use has fallen 15% annually since 2014 and more. Read the full coverage here: Enbrel, Stelara to be discounted nearly 70% through Medicare price negotiations Opioid use has fallen 15% annually since 2014 in autoimmune rheumatic disease Inhibitor class PsO treatments exhibit similar efficacy in mitigating PsA risk S100 protein levels predict abatacept response in juvenile idiopathic arthritis Izokibep shows early promise in hidradenitis suppurativa References: Brunner HI, et al. Arthritis Res Ther. 2024;doi:10.1186/s13075-024-03347-0. Falasinnu T, et al. Lancet Rheumatol. 2024;doi:10.1016/S2665-9913(24)00120-6. Press Release Press Release Tsai SHL, et al. J Am Acad Dermatol . 2024;doi:10.1016/j.jaad.2024.07.1473 .…
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Healio Minute
1 Lung Cancer Edition: Top Headlines for Week of August 12, 2024 15:14
15:14 Lire Plus Tard Lire Plus Tard Des listes J'aime Aimé15:14
Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, low education level raises follow-up risk in screening program, screening judgement strongly influenced by clinicians and more. Read the full coverage here: Low education level raises risk for loss to follow-up in lung cancer screening program Lung cancer screening judgement strongly influenced by clinicians Occupational benzene exposure heightens lung cancer likelihood Chemotherapy plus nintedanib has ‘promising’ efficacy in small cell lung cancer with IPF Blood biomarker identifying benign lung nodules performs well across subgroups References: Ikeda S, et al. Ann Am Thorac Soc. 2024;doi:10.1513/AnnalsATS.202311-941OC. Long KJ, et al. CHEST. 2023;doi:10.1016/j.chest.2023.06.037. Mugutso E, et al. Ann Am Thorac Soc. 2023;doi:10.1513/AnnalsATS.202304-348RL. Núñez ER, et al. Am J Respir Crit Care Med. 2024;doi:10.1164/rccm.202301-0155OC. Wan W, et al. Am J Respir Crit Care Med. 2024;doi:10.1164/rccm.202306-0942OC.…
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Healio Minute
1 DME/Retina Edition: Top Headlines for Week of August 5, 2024 11:23
11:23 Lire Plus Tard Lire Plus Tard Des listes J'aime Aimé11:23
Lire Plus Tard Lire Plus Tard Des listes J'aime AiméIn this edition, sozinibercept combination therapy shows durability, comparable improvements with aflibercept and more. Read the full coverage here: Sozinibercept combination therapy shows durability in patients with DME, neovascular AMD VIDEO: Comparable improvements seen with aflibercept 8 mg vs. 2 mg in DME DPP-IV, SGLT2 and GLP-1 drugs do not increase risk for diabetic macular edema Eluminex doses first patient in phase 1b trial of EB-105 for diabetic macular edema VIDEO: Port delivery system maintains visual, anatomic improvements in DME at 2 years References: Awh C. Port delivery system with ranibizumab for continuous treatment of diabetic macular edema: First readout of the phase 3 Pagoda trial year 2 results. Presented at: American Society of Retina Specialists annual meeting; July 17-20, 2024; Stockholm. Do D. Outcomes of patients with DME and baseline BCVA of 20/50 or worse or 20/40 or better treated with aflibercept 8 mg and 2 mg in the phase 2/3 PHOTON trial. Presented at: American Society of Retina Specialists annual meeting; July 17-20, 2024; Stockholm. Phu A, et al. J Diabetes Complications. 2024;doi:10.1016/j.jdiacomp.2024.108808. Press Release Steinle NC. Durability of combination therapy of sozinibercept (OPT-302), an anti-VEGF-C/-D ‘trap’ with ranibizumab in nAMD or aflibercept in DME. Presented at: American Society of Retina Specialists annual meeting; July 17-20, 2024; Stockholm.…
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