BC 048 – Efficacité et sécurité de l’acide tranexamique en péri-opératoire (étude POISE-3)

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Dans cette 48e baladodiffusion, le Dr Luc Lanthier discute d’acide tranexamique en péri-opératoire, en plus de réviser la littérature médicale de mars et avril 2022.

Quiz clinique (4 min 48), étude principale (5 min 20), critique (23 min 55), autres articles (30 min 56), réponse au quiz clinique (33 min 46)

Référence principale :

Devereaux PJ, Marcucci M, Painter TW, Conen D, Lomivorotov V, Sessler DI, et al. Tranexamic Acid in Patients Undergoing Noncardiac Surgery. N Engl J Med. 2022. doi: 10.1056/NEJMoa2201171. PubMed PMID: 35363452.

Articles associés :

Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (VISION) Study Investigators, Spence J, LeManach Y, Chan MTV, Wang CY, Sigamani A, Xavier D, et al. Association between complications and death within 30 days after noncardiac surgery. CMAJ. 2019;191(30):E830-E837. PubMed PMID: 31358597.

Roshanov PS, Guyatt GH, Tandon V, Borges FK, Lamy A, Whitlock R, et al. Preoperative prediction of Bleeding Independently associated with Mortality after noncardiac Surgery (BIMS): an international prospective cohort study. Br J Anaesth. 2021;126(1):172-80. PubMed PMID: 32718723.

Perioperative Risk Prediction – Tools for predicting complications in surgical patients

US Preventive Services Task Force, Davidson KW, Barry MJ, Mangione CM, Cabana M, Chelmow D, Coker TR, Davis EM, Donahue KE, Jaén CR, Krist AH, Kubik M, Li L, Ogedegbe G, Pbert L, Ruiz JM, Stevermer J, Tseng CW, Wong JB. Aspirin Use to Prevent Cardiovascular Disease: US Preventive Services Task Force Recommendation Statement. JAMA. 2022;327(16):1577-1584. PubMed PMID: 35471505.

Autres articles d’intérêt :

Finfer S, Micallef S, Hammond N, Navarra L, Bellomo R, Billot L, et al. Balanced Multielectrolyte Solution versus Saline in Critically Ill Adults. N Engl J Med. 2022;386(9):815-26. PubMed PMID: 35041780.

Banovic M, Putnik S, Penicka M, Doros G, Deja MA, Kockova R, et al. Aortic Valve Replacement Versus Conservative Treatment in Asymptomatic Severe Aortic Stenosis: The AVATAR Trial. Circulation. 2022;145(9):648-58. PubMed PMID: 34779220.

Piccini JP, Caso V, Connolly SJ, Fox KAA, Oldgren J, Jones WS, et al. Safety of the oral factor XIa inhibitor asundexian compared with apixaban in patients with atrial fibrillation (PACIFIC-AF): a multicentre, randomised, double-blind, double-dummy, dose-finding phase 2 study. Lancet. 2022;399(10333):1383-90. PubMed PMID: 35385695.

Guides de pratique :

Campbell JR, Pease C, Daley P, Pai M, Menzies D. Chapter 4: Diagnosis of tuberculosis infection. Canadian Journal of Respiratory, Critical Care, and Sleep Medicine. 2022;6(sup1):49-65. doi: 10.1080/24745332.2022.2036503.

Johnston JC, Cooper R, Menzies D. Chapter 5: Treatment of tuberculosis disease. Canadian Journal of Respiratory, Critical Care, and Sleep Medicine. 2022;6(sup1):66-76. doi: 10.1080/24745332.2022.2036504.

Qaseem A, Etxeandia-Ikobaltzeta I, Lin JS, Fitterman N, Shamliyan T, Wilt TJ, et al. Diagnosis and Management of Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians. Ann Intern Med. 2022;175(3):399-415. PubMed PMID: 35038273.

Shaheen NJ, Falk GW, Iyer PG, Souza RF, Yadlapati RH, Sauer BG, et al. Diagnosis and Management of Barrett’s Esophagus: An Updated ACG Guideline. Am J Gastroenterol. 2022;117(4):559-87. PubMed PMID: 35354777.

Abraham NS, Barkun AN, Sauer BG, Douketis J, Laine L, Noseworthy PA, et al. American College of Gastroenterology-Canadian Association of Gastroenterology Clinical Practice Guideline: Management of Anticoagulants and Antiplatelets During Acute Gastrointestinal Bleeding and the Periendoscopic Period. Am J Gastroenterol. 2022;117(4):542-58. PubMed PMID: 35297395.

Capsule méthodologique :

O’Fee K, Deych E, Ciani O, Brown DL. Assessment of Nonfatal Myocardial Infarction as a Surrogate for All-Cause and Cardiovascular Mortality in Treatment or Prevention of Coronary Artery Disease: A Meta-analysis of Randomized Clinical Trials. JAMA Intern Med. 2021;181(12):1575-1587. PubMed PMID: 34694318.

Référence du quiz clinique :

Warren J, Cooper B, Jermakoff A, Knott JC. Antacid Monotherapy Is More Effective in Relieving Epigastric Pain Than in Combination With Lidocaine: A Randomized Double-blind Clinical Trial. Acad Emerg Med. 2020;27(9):905-909. PubMed PMID: 32602148.

48 episodes