BC 036 – Colchicine chez les sujets avec maladie coronarienne stable (étude LoDoCo2)

BaladoCritique - club de lecture médical

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Dans cette 36e baladodiffusion, les Drs Luc Lanthier et Charles Dussault discutent de l’efficacité de la colchicine chez les sujets avec maladie coronarienne athérosclérotique chronique et stable, en plus de réviser la littérature médicale d’août 2020.

Quiz clinique (2min25), étude principale (2min49), critique (19min50), autres articles (25min20), réponse au quiz clinique (30min59)

Référence principale

Nidorf SM, Fiolet ATL, Mosterd A, Eikelboom JW, Schut A, Opstal TSJ, et al. Colchicine in Patients with Chronic Coronary Disease [published online ahead of print, 2020 Aug 31]. N Engl J Med. 2020;10.1056/NEJMoa2021372. PubMed PMID : 32865380.

Articles associés

WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group, Sterne JAC, Murthy S, et al. Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis [published online ahead of print, 2020 Sep 2]. JAMA. 2020;10.1001/jama.2020.17023. PubMed PMID : 32876694.

Gaudino M, Arvind V, Hameed I, Di Franco A, Spadaccio C, Bhatt DL, et al. Effects of the COVID pandemic on active non-COVID clinical trials. [published online ahead of print, 2020 Jul 29]. J Am Coll Cardiol. 2020;S0735-1097(20)36164-7. PubMed PMID : 32745501.

Nidorf SM, Eikelboom JW, Budgeon CA, Thompson PL. Low-dose colchicine for secondary prevention of cardiovascular disease. J Am Coll Cardiol. 2013;61(4):404-410. PubMed PMID: 23265346.

Ridker PM, Everett BM, Pradhan A, MacFadyen JG, Solomon DH, Zaharris E, et al. Low-Dose Methotrexate for the Prevention of Atherosclerotic Events. N Engl J Med. 2019;380(8):752-62. PubMed PMID: 30415610.

Tardif J-C, Kouz S, Waters DD, Bertrand OF, Diaz R, Maggioni AP, et al. Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction. N Engl J Med. 2019;381(26):2497-2505. PubMed PMID : 31733140.

Tong DC, Quinn S, Nasis A, et al. Colchicine in Patients with Acute Coronary Syndrome: The Australian COPS Randomized Clinical Trial [published online ahead of print, 2020 Aug 29]. Circulation. 2020;10.1161/CIRCULATIONAHA.120.050771. PubMed PMID : 32862667.

Autres articles d’intérêt

Kirchhof P, Camm AJ, Goette A, Brandes A, Eckardt L, Elvan A, et al. Early Rhythm-Control Therapy in Patients with Atrial Fibrillation [published online ahead of print, 2020 Aug 29]. N Engl J Med. 2020;10.1056/NEJMoa2019422. PubMed PMID : 32865375.

Packer M, Anker SD, Butler J, Filippatos G, Pocock SJ, Carson P, et al. Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure [published online ahead of print, 2020 Aug 29]. N Engl J Med. 2020;10.1056/NEJMoa2022190. PubMed PMID : 32865377.

Brouwer J, Nijenhuis VJ, Delewi R, et al. Aspirin with or without Clopidogrel after Transcatheter Aortic-Valve Implantation [published online ahead of print, 2020 Aug 30]. N Engl J Med. 2020;10.1056/NEJMoa2017815. PubMed PMID : 32865376

Webb E, Neeman T, Bowden FJ, Gaida J, Mumford V, Bissett B. Compression Therapy to Prevent Recurrent Cellulitis of the Leg. N Engl J Med. 2020;383(7):630-9. PubMed PMID : 32786188.

Nicholson BD, Aveyard P, Price SJ, Hobbs FR, Koshiaris C, Hamilton W. Prioritising primary care patients with unexpected weight loss for cancer investigation: diagnostic accuracy study. BMJ. 2020;370:m2651. PubMed PMID : 32816714.

Guides de pratique

Wharton S, Lau DCW, Vallis M, Sharma AM, Biertho L, Campbell-Scherer D, et al. Obesity in adults: a clinical practice guideline. CMAJ. 2020;192(31):E875-E91. PubMed PMID : 32753461.

Sandhu RK, Raj SR, Thiruganasambandamoorthy V, Kaul P, Morillo CA, et al. Canadian Cardiovascular Society Clinical Practice Update on the Assessment and Management of Syncope. Can J Cardiol. 2020;36(8):1167-77. PubMed PMID : 32624296.

Références du quiz clinique

Hydes TJ, Burton R, Inskip H, Bellis MA, Sheron N. A comparison of gender-linked population cancer risks between alcohol and tobacco: how many cigarettes are there in a bottle of wine?. BMC Public Health. 2019;19(1):316. PubMed PMID : 30917803.

GBD 2016 Alcohol Collaborators. Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2018;392(10152):1015-1035. PubMed PMID : 30146330.

Manthey J, Shield KD, Rylett M, Hasan OSM, Probst C, Rehm J. Global alcohol exposure between 1990 and 2017 and forecasts until 2030: a modelling study. Lancet. 2019;393(10190):2493-2502. PubMed PMID : 31076174.

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