BC 029 – Efficacité et innocuité de la colchicine après un infarctus du myocarde (étude COLCOT)

BaladoCritique - club de lecture médical

Dans cette 29e baladodiffusion, les Drs Gabriel Huard et Charles Dussault discutent de l’efficacité de la colchicine après un infarctus du myocarde (étude COLCOT), en plus de réviser la littérature médicale d’octobre et de novembre 2019.

Quiz clinique (1 min 05), étude principale (1 min 47), critique (15 min 37), autres articles (18 min 40), réponse au quiz clinique (30 min 52)

Référence principale

Tardif J-C, Kouz S, Waters DD, Bertrand OF, Diaz R, Maggioni AP, et al. Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction. N Engl J Med 2019. doi: 10.1056/NEJMoa1912388. PubMed PMID : 31733140.

Articles associés

Newby LK. Inflammation as a Treatment Target after Acute Myocardial Infarction. N Engl J Med. 2019. doi: 10.1056/NEJMe1914378. PubMed PMID : 31733139.

Ridker PM, Everett BM, Thuren T, et al. Antiinflammatory therapy with canakinumab for atherosclerotic disease. N Engl J Med 2017;377(12):1119-31. PubMed PMID : 28845751.

Ridker PM, Everett BM, Pradhan A, et al. Low-dose methotrexate for the prevention of atherosclerotic events. N Engl J Med 2019;380(8):752-62. PubMed PMID : 30415610.

Nidorf SM, Eikelboom JW, Budgeon CA, Thompson PL. Low-dose colchicine for secondary prevention of cardiovascular disease. J Am Coll Cardiol. 2013;61(4): 404-10. PubMed PMID : 23265346.

Dangas GD, Tijssen JGP, Wöhrle J, Søndergaard L, Gilard M, Möllmann H, et al. A controlled trial of rivaroxaban after transcatheter aortic-valve replacement. N Engl J Med. 2019. doi: 10.1056/NEJMoa1911425. PubMed PMID : 31733180.

Kang D-H, Park S-J, Lee S-A, Lee S, Kim D-H, Kim H-K, et al. Early surgery or conservative care for asymptomatic aortic stenosis. N Engl J Med. 2019. doi: 10.1056/NEJMoa1912846. PubMed PMID : 31733181.

Amarenco P et al. A comparison of two LDL cholesterol targets after ischemic stroke. N Engl J Med 2019. doi: 10.1056/NEJMoa1910355. PubMed PMID : 31738483.

Autres articles d’intérêt

Octobre

Solomon SD, McMurray JJV, Anand IS, Ge J, Lam CSP, Maggioni AP, et al. Angiotensin–Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction. N Engl J Med. 2019;381(17):1609‑20. PubMed PMID : 31475794.

Steg PG, Bhatt DL, Simon T, Fox K, Mehta SR, Harrington RA, et al. Ticagrelor in Patients with Stable Coronary Disease and Diabetes. N Engl J Med. 2019;381(14):1309‑20. PubMed PMID : 31475798.

Novembre

Kearon C, de Wit K, Parpia S, Schulman S, Afilalo M, Hirsch A, et al. Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability. N Engl J Med. 2019;381(22):2125‑34. PubMed PMID : 31774957.

Ordi-Ros J, Sáez-Comet L, Pérez-Conesa M, Vidal X, Riera-Mestre A, Castro-Salomó A, et al. Rivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome: A Randomized Noninferiority Trial. Ann Intern Med. 2019;171(10):685-94. PubMed PMID : 31610549.

Guides de pratique

Octobre

Metlay JP, Waterer GW, Long AC, Anzueto A, Brozek J, Crothers K, et al. Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America. Am J Respir Crit Care Med. 2019;200(7):e45‑67. PubMed PMID : 31573350.

Helsingen LM, Vandvik PO, Jodal HC, Agoritsas T, Lytvyn L, Anderson JC, et al. Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: a clinical practice guideline. BMJ. 2019;l5515. PubMed PMID : 31578196.

Novembre

Asgar AW, Ouzounian M, Adams C, Afilalo J, Fremes S, Lauck S, et al. 2019 Canadian Cardiovascular Society Position Statement for Transcatheter Aortic Valve Implantation. Can J Cardiol. 2019;35(11):1437‑48. PubMed PMID : 31679616.

Tektonidou MG, Andreoli L, Limper M, Amoura Z, Cervera R, Costedoat-Chalumeau N, et al. EULAR recommendations for the management of antiphospholipid syndrome in adults. Ann Rheum Dis. 2019;78(10):1296‑304. PubMed PMID : 31092409.

Birtwhistle R, Morissette K, Dickinson JA, Reynolds DL, Avey MT, Domingo FR, et al. Recommendation on screening adults for asymptomatic thyroid dysfunction in primary care. CMAJ. 2019;191(46):E1274‑80. PubMed PMID : 31740537.

Référence du quiz clinique

Metlay JP, Waterer GW, Long AC, Anzueto A, Brozek J, Crothers K, et al. Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America. Am J Respir Crit Care Med. 2019;200(7):e45‑67. PubMed PMID : 31573350.